Van de Ven Double Halts The Toffees' Run at New Home Ground
The Dutch defender became the initial backline player to score twice in a English top-flight game for Spurs since the Belgian defender in March 2013.
At a glance
Micky Van de Ven nods into the net two times in first half
Everton's Jake O'Brien has equalizer disallowed after video check
Pape Matar Sarr nets final goal in 89th minute
This loss is Everton's initial at Hill Dickinson Stadium
Micky van de Ven scored on two occasions as Tottenham prolonged their winning streak on the road in the Premier League and handed the Toffees their initial loss at Hill Dickinson Stadium.
The Toffees were unbeaten in their five previous fixtures at their recently opened stadium at Bramley-Moore Dock, having departed Goodison Park behind after 133 years at the conclusion of last season.
But Spurs captain Van de Ven struck on two occasions from corners in the first half to place their impressive record at jeopardy, and they were unable to turn it around before Pape Matar Sarr - assisted by ex-Everton forward Richarlison - nodded in a final goal to put the game to bed.
Jake O'Brien thought he had levelled the scores a short while after Van de Ven's opener, directing a powerful header past the Spurs keeper from an Everton corner.
The Portuguese striker, meanwhile, failed to convert a number of opportunities, while the Italian goalkeeper made a series of fine saves to guarantee Tottenham went five matches on the road unbeaten in the Premier League.
But the video assistant referee intervened, advising Craig Pawson to check the goal on the pitchside monitor and the official decided that Jack Grealish and the attacker were in an illegal position and had impeded with the Spurs keeper.
This victory moves the manager's team up to third in the Premier League, five points off local foes and leaders the Gunners.
The Merseyside club remain in 14th position and sit six points ahead of the drop zone.
Tottenham analysis: The defender fulfils duties at each end of the field
Following a uninspiring midweek display in the Champions League against the French side, where they mustered a only two shots on goal, the manager opted for Randal Kolo Muani in attack instead of former Toffees player the Brazilian.
The summer signing was unable to influence the game before being replaced for the substitute after 60 minutes on the field, but it emerged he wasn't needed in the final outcome.
Defender the Dutchman converted into an offensive threat to be reckoned with.
Tottenham's opening strike came from a well-worked set-piece play, with Rodrigo Bentancur heading the ball back across the six-yard box for an free the defender to head home.
And Ven de Ven - filling in as captain in the Argentine's absence - added his second in added time as he rose above Jordan Pickford to head home.
Van de Ven was equally impressive in defensive duties, combining well with Kevin Danso as the pair dealt superbly with the numerous deliveries sent their way by Everton.
Toffees breakdown: Toffees lacking finishing touch
Everton's new home had been a happy hunting ground, but it appears the freshness may have faded slightly and fans flocked to the exits after Sarr's third for Tottenham.
The break in the team's unbeaten home run won't be a major worry for the manager, but their attacking woes are.
The forward and Thierno Barry - the Everton's two established strikers - had scored just a single goal combined before the weekend's outing.
And they were failed to contribute to that poor record on a damp and dreary night on Merseyside.
The striker's form was epitomized when he chose to bicycle-kick a golden opportunity from close range, despite having room and time to readjust for a simpler attempt that would have tested the keeper.
The substitute, too, was unable to make an impact after replacing the starter in the 65th minute.
It was not for a shortage of opportunity. The majority of Everton's attacks came through the winger and the forward, who relentlessly delivered dangerous balls into the Tottenham box.
What next for these two sides?
Everton: Moyes' men head to Sunderland in the top flight on early November at 20:00 GMT.
Tottenham: Spurs travel to St James' Park on late October for their next round Carabao Cup tie against the Magpies.